Estas canciones son vitales para un conocimiento básico de la historia del «Blues», el significado histórico, la definición de una época, la influencia y, en menor grado, la popularidad duradera son los puntos tenidos en cuenta.

En algunos casos, la composición recibió el crédito de la lista en lugar del artista que pudo haber sido más conocido por la canción.

  1. Memphis Blues – W.C. Handy
  2. Crazy Blues – Mamie Smith
  3. Pine Top Boogie – Pine Top Smith
  4. Dust My Broom – Elmore James
  5. Boogie Chillun – John Lee Hooker
  6. Mannish Boy – Muddy Waters
  7. Stormy Monday – T-Bone Walker
  8. Hellhound On My Trail – Robert Johnson
  9. Spoonful – Willie Dixon
  10. The Thrill Is Gone – B.B. King
  11. Good Morning Little Schoolgirl – Sonny Boy Williamson I
  12. Born Under A Bad Sign – Albert King
  13. Forty Four Blues – Roosevelt Sykes
  14. Smokestack Lightnin’ – Howlin’ Wolf
  15. Statesboro Blues – Taj Mahal
  16. Hoochie Coochie Man – Muddy Waters
  17. Juke – Little Walter
  18. The Little Red Rooster – Willie Dixon
  19. Come In My Kitchen – Robert Johnson
  20. I’m a King Bee – Slim Harpo
  21. The Things That I Used To Do – Guitar Slim
  22. Back Door Man – Willie Dixon
  23. It’s My Own Fault – B.B. King
  24. I’m Tore Down – Freddie King
  25. T-Bone Blues – T-Bone Walker
  26. Sweet Home Chicago – Robert Johnson
  27. Preaching The Blues – Son House
  28. Nobody Knows You When You’re Down & Out – Bessie Smith
  29. I Can’t Be Satisfied – Muddy Waters
  30. Shake Your Moneymaker – Elmore James
  31. Matchbox Blues – Blind Lemon Jefferson
  32. Hideaway – Freddie King
  33. How Long, How Long Blues – Leroy Carr & Scrapper Blackwell
  34. Five Long Years – Eddie Boyd
  35. Red House – Jimi Hendrix
  36. Cross Road Blues – Robert Johnson
  37. All Your Love – Magic Sam
  38. Give Me Back My Wig – Lightnin’ Hopkins
  39. Reconsider Baby – Lowell Fulson
  40. Worried Life Blues – Sleepy John Estes
  41. If Trouble Was Money – Albert Collins
  42. I Ain’t Superstitious – Willie Dixon
  43. Sweet Black Angel – Robert Nighthawk
  44. I Know What You’re Putting Down – Louis Jordan
  45. Black Snake Moan – Blind Lemon Jefferson
  46. Ball and Chain – Big Mama Thornton
  47. Further On Up The Road – Bobby ‘Blue’ Bland
  48. I Can’t Quit You Baby – Otis Rush
  49. Boom Boom – John Lee Hooker
  50. Born In Chicago – Paul Butterfield Blues Band
  51. Let The Good Times Roll – Louis Jordan
  52. Pride and Joy – Stevie Ray Vaughan
  53. Pony Blues – Charley Patton
  54. The Sky Is Crying – Elmore James
  55. Catfish Blues – Robert Petway
  56. Highway 49 – Big Joe Williams
  57. See That My Grave Is Kept Clean – Blind Lemon Jefferson
  58. Blues Before Sunrise – Leroy Carr & Scrapper Blackwell
  59. Baby Please Don’t Go – Big Joe Williams
  60. Bumble Bee – Memphis Minnie
  61. I’m Ready – Muddy Waters
  62. It Hurts Me Too – Elmore James
  63. Stop Breakin’ Down – Robert Johnson
  64. Texas Flood – Stevie Ray Vaughan
  65. I’m In The Mood – John Lee Hooker
  66. Me and The Devil Blues – Robert Johnson
  67. The Walkin’ Blues – Taj Mahal
  68. ‘Taint Nobody’s Bizness If I Do – Bessie Smith
  69. It’s Tight Like That – Tampa Red
  70. Love In Vain – Robert Johnson
  71. Evil – Willie Dixon
  72. Baby Scratch My Back – Slim Harpo
  73. Wang Dang Doodle – Koko Taylor
  74. On The Road Again – Canned Heat
  75. Rock Me Mama – Arthur ‘Big Boy’ Crudup
  76. Three O’Clock Blues – B.B. King
  77. Tomorrow Night – Lonnie Johnson
  78. Boom Boom Out Go The Lights – Little Walter
  79. The Same Thing – Willie Dixon
  80. West Coast Blues – Blind Blake
  81. How Many More Years – Howlin’ Wolf
  82. Give Me Back My Wig – Hound Dog Taylor
  83. Rollin & Tumblin – Elmore James
  84. Everyday I Have The Blues – B.B. King
  85. Messin Around – Memphis Slim
  86. Blues After Hours – Pee Wee Crayton
  87. Eyesight To The Blind – Sonny Boy Williamson II
  88. CC Rider – Ma Rainey
  89. I’m Tired – Savoy Brown
  90. Graveyard Dream Blues – Ida Cox
  91. Beaver Slide Rag – Peg Leg Howell
  92. Key To The Highway – Big Bill Broonzy
  93. Messin’ With The Kid – Junior Wells
  94. The Seventh Son – Willie Dixon
  95. As The Years Go Passing By – Gary Moore
  96. We’re Gonna Make It – Little Milton
  97. Drinking Wine Spo-Dee-O-Dee – Stick McGhee
  98. Hard Luck Blues – Roy Brown
  99. Black Magic Woman – Fleetwood Mac
  100. Stone Crazy – Buddy Guy